Resveratrol Side Effects

If you’re considering taking resveratrol as a supplement, you may have heard about its potential benefits, such as reducing inflammation, improving heart health, and protecting against certain cancers. However, you may need to learn that there can be possible Resveratrol side effects associated with its supplementation

Resveratrol side effects

Resveratrol is a naturally occurring compound found in grapes, berries, and peanuts, and it’s also available in supplement form. While some research suggests that resveratrol may offer health benefits, it’s essential to be aware of the potential risks before taking it.

  • Gastrointestinal issues such as diarrhea, nausea, and stomach cramps
  • Headaches
  • Dizziness
  • Allergic reactions
  • Interference with blood clotting

While these side effects are uncommon and generally not serious, it’s still important to be aware of them. Additionally, there may be certain groups of people who should avoid resveratrol supplementation altogether, such as those who are pregnant or breastfeeding.

In the following sections, we’ll take a closer look at the potential risks associated with resveratrol supplementation and explore the adverse effects that can occur.

Key Takeaways:

  • Resveratrol supplementation can have potential side effects, such as gastrointestinal issues, headaches, and allergic reactions.
  • It’s essential to be aware of these risks before taking resveratrol as a supplement.
  • Certain groups of people, such as pregnant or breastfeeding women, may want to avoid resveratrol supplementation altogether.

Understanding Resveratrol and Its Potential Risks

While resveratrol has been touted for its potential health benefits, such as reducing inflammation and improving heart health, it is essential to be aware of the potential risks associated with its use.

Some health concerns regarding resveratrol and its safety as a supplement have been raised. While resveratrol is naturally found in certain foods, such as grapes and red wine, the safety of taking concentrated doses as a supplement has not been confirmed.

While early research suggests that resveratrol may have anti-cancer properties, the research is not (yet) conclusive. Additionally, some studies have found that resveratrol may interfere with certain medications, such as blood thinners, and may have negative interactions with other supplements1.

It is also important to note that the possible benefits of resveratrol, such as improving heart health, can be achieved through other means, such as a healthy diet and regular exercise.

Before taking resveratrol as a supplement, it is essential to consult with a healthcare professional to determine if it is safe for you.

resveratrol and health concerns

While resveratrol may have some potential health benefits, weighing these benefits against the possible drawbacks and risks associated with its use is essential.

Exploring the Resveratrol Side Effects

While resveratrol has been touted for its potential health benefits, it has potential risks. There have been some documented adverse effects associated with resveratrol supplementation.

  • Gastrointestinal issues such as diarrhea, nausea, and stomach cramps
  • Headaches
  • Dizziness
  • Allergic reactions
  • Interference with blood clotting

It is worth noting that many of the potential adverse effects associated with resveratrol supplementation are relatively mild and go away on their own. However, it is still important to use caution and speak with a healthcare professional before starting resveratrol supplementation. 2,3

The following section will delve more deeply into the recommended dosages for resveratrol supplements and explore the potential benefits of taking the appropriate amount of trans-resveratrol.

Adverse Effects of Resveratrol

Dosage and Benefits

Regarding resveratrol supplements, one of the most critical considerations is dosage. Taking the appropriate dosage to reap the potential benefits while minimizing potential risks is crucial.

According to scientific research, the ideal daily resveratrol dosage is between 150mg and 445mg. It’s important to note that this range applies only to trans-resveratrol, the natural compound found in red wine, peanuts, and berries.

Dosage Range (mg/day)Potential Benefits
150-250mgImproved cardiovascular health, including lower blood pressure and reduced risk of heart disease
250-445mgEnhanced cognitive function, better insulin sensitivity, and reduced inflammation

So, why take trans-resveratrol in the first place? There are several potential benefits to adding this supplement to your daily routine:

  • Improved cardiovascular health
  • Reduced inflammation
  • Better insulin sensitivity
  • Enhanced cognitive function

While more research is needed to understand the extent of these benefits fully, early findings are promising. It’s important to note that proper diet and exercise are also crucial factors in maintaining overall health and wellness.

The Safety of Resveratrol Supplementation

The Importance of Responsible Use

The safety of resveratrol supplementation is also heavily dependent on responsible use. It is crucial to follow the recommended dosage guidelines and stay within the maximum dosage recommended by the manufacturer.

It is also vital to choose a reputable brand and ensure that the supplement does not contain harmful additives or contaminants. By doing so, you can minimize the risks associated with resveratrol supplementation.


Resveratrol supplementation has shown potential health benefits, but it is essential to understand the possible risks and side effects before deciding. As mentioned in the previous sections, some adverse effects have been reported, and responsible use should be encouraged.

Consulting with healthcare professionals is always recommended before starting any new supplement regimen. Additionally, it is essential to ensure that the dosage taken is appropriate and within safe limits.

If taken correctly, trans-resveratrol can offer various benefits, including potential cardiovascular benefits and anti-inflammatory effects. However, it is essential to remain informed and cautious, especially when considering long-term use.

In conclusion, the potential risks of resveratrol supplementation should not be ignored, but with responsible use and proper consultation, it can be a beneficial addition to a healthy lifestyle.


Who Shouldn’t Take Resveratrol?

People with bleeding problems should talk to a doctor before taking resveratrol. Also, if you’re going to have surgery, you should stop taking resveratrol two weeks before and not start again until two weeks after the surgery to help prevent bleeding.

Don’t use resveratrol supplements or eat too many foods with resveratrol if you’re pregnant or breastfeeding. The safety of resveratrol hasn’t been proven in these cases. Also, children should not take resveratrol.

What Side Effects Can Resveratrol Have?

No harmful effects from resveratrol in humans have been found. We’re still not sure about the long-term side effects. In a short study in 2011 with overweight people who took 150 mg of resveratrol daily, no bad reactions were reported..4

Is resveratrol supplementation safe?

Resveratrol supplementation can be safe when used responsibly, but it is essential to consider potential risks and consult a healthcare professional. It is also advisable to purchase resveratrol supplements from reputable sources to ensure quality and purity.

Can resveratrol supplementation benefit individuals with specific health conditions?

Resveratrol may have potential benefits for heart health and insulin sensitivity, which could be advantageous for individuals with cardiovascular concerns or diabetes. However, it should be used under medical advice in such cases.


  1. Apoptotic Cell Death Induced by Resveratrol Is Partially Mediated by the Autophagy Pathway in Human Ovarian Cancer Cells ↩︎
  2. Potential Adverse Effects of Resveratrol: A Literature Review ↩︎
  3. Resveratrol Side Effects and Health Hazards ↩︎
  4. trans-Resveratrol in Nutraceuticals: Issues in Retail Quality and Effectiveness ↩︎